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Published preclinical work has used diet-induced-obese and GLP-1R knockout rodent models alongside indirect calorimetry and pair-feeding designs as experimental tools to study how the three receptor pathways relate to measured signaling readouts, plus cell and tissue systems probing hepatic lipid handling
doi: 10.1038/sj.onc.1210796 18 BartoliniD.StabileA
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