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doi: 10.1210/en.2017-00461 97 LigumskyHWolfIIsraeliSHaimsohnMFerberSKarasikAet al
Deficiencies may manifest as neurological symptoms, including numbness, tingling, and cognitive disturbances
Unlike Melanotan 2, which non-selectively activates MC1R, MC3R, MC4R, and MC5R, Melanotan 1s selectivity for MC1R makes it a valuable research tool for isolating melanocortin-1 receptor biology from the broader melanocortin receptor system
(30,31) The authors acknowledged several limitations, including the use of a national patient database, which restricted their ability to control for prior diabetes management and preoperative glycemic control
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