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Based on todays evidence: Injections produce the highest overall weight loss Oral options offer unmatched convenience with strong early results Both are effective for people with obesity or type 2 diabetes For many patients, the choice is not just which is stronger? But its which is easier to stay on long-term? Side Effects: What the Study Found The clinical trial results for GLP-1 treatments show that orforglipron has a similar side-effect pattern to other GLP-1 receptor agonists: most issues are gastrointestinal and mild to moderate
[1,2] When overweight categories are included, the burden becomes even more striking: since 2022, approximately 40% of Canadian men and 30% of women are classified as overweight, meaning that nearly three in four men and two in three women fall within BMI ranges associated with increased health risk
5, 196 (2014) , P
Frontiers in Pharmacology, 13, 1026182
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