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The lack of normalization of BDNF and NGF levels suggests that LipRSV did not engage plasticity-related pathways essential for behavioral rescue, reinforcing the notion that antioxidant strategies alone may be insufficient in ASD models

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ASS1 expression has been reported to be decreased or even abolished in many cancers (Dillon et al., 2004), especially in malignant melanoma (Feun et al., 2012), HCC (Delage et al., 2010), and prostate cancer (Kim et al., 2009), which are thought of as arginine-auxotrophic cancers because of the inability to synthesize arginine and resulting susceptibility to arginine-deprivation therapy