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A study published in The Journal of Clinical Pharmacology investigated the impact of semaglutide, the active ingredient in Ozempic, on the bioavailability of a combined oral contraceptive containing ethinylestradiol and levonorgestrel
Acknowledgements The authors are also grateful to the staff of the Institutes of Advanced Technology, Department of Chemistry UPM for their help in this research, Institute of Bioscience (IBS/UPM) for technical assistance
Protein pellets were extracted from these aliquots by two rounds of centrifugation at 16,000 rpm x g, first for 10 minutes, and then for 5 minutes after washing with 50 L of chilled acetone
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