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It remains unclear whether there is a relationship between the central actions of peripheral GLP-1 and the GLP-1-producing neurons in the brain stem, but it is clear that one of the most important actions of peripheral GLP-1 is to regulate food intake in agreement with its ileal brake function
It is usually taken once daily, either before breakfast or 1-2 hours after breakfast
Beyond glycaemic control and weight reduction, semaglutide has shown additional benefits in clinical studies
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