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Generally, researchers restart the titration schedule with retatrutide regardless of their previous dose, though some experienced practitioners adjust based on their GLP-1 tolerance history
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The steelman argument against switching: A thoughtful clinician might argue against switching in the following scenario: a patient on Wegovy 2.4 mg has lost 12% of body weight over 6 months, tolerates the medication well, and has 8% more to lose to reach goal weight
