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[4] Why Vitamin B12 Can Cause Gastrointestinal Symptoms The mechanisms underlying gastrointestinal side effects from vitamin B12 supplementation are not fully established, but several factors may contribute to stomach discomfort in susceptible individuals

It is particularly common in individuals with certain risk factors, including those who have undergone gastric or small intestine resections, have inflammatory bowel disease, use metformin or proton pump inhibitors, follow a vegan diet, or are older than 75 years

When to Prioritize B6 : Vitamin B6 supplementation may particularly benefit individuals experiencing nausea, fatigue, or mood fluctuations while using semaglutide

Knowing the key rules for B12 injections helps doctors give better care to those with a B12 deficiency