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L-carnitine is given to patients receiving dialysis for kidney failure and is considered very safe.L-carnitine (LC) administration has been recommended for specific indications in dialysis patients, including epoetin-resistant anemia, intradialytic hypotension, cardiomyopathy, fatigue, muscle weakness, and exercise performance

64 reported that in Bacillus megaterium tyrosinase (PDB: 3NM8), the pyranose glucoside part of arbutin faces the metal active site

Klotho, an anti-aging protein, was shown to attenuate mitochondrial injury, cellular senescence, and renal fibrosis induced by Wnt1 and Wnt9a in both unilateral ischemia-reperfusion mice and cultured human renal tubular epithelial cells (205)

Lamport DJ, Breese E, Giao MS, Chandra S, Orchard F