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SOD1 integrates signals from oxygen and glucose to repress respiration
The landmark 2017 Cell study (Baar MP et al., PMID: 28340339) demonstrated that: (1) FOXO4 protein specifically accumulates in senescent cells where it binds to p53 and prevents p53 from triggering apoptosis (this is the specific mechanism being targeted)
Schwarzenegger told the press, I have to be very honest, that this was the highest level of competition that I have ever faced in any competition in my life His disregard to the drama in his press conference further enraged his fellow competitors
Neurobiol Aging 76:201207
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