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There are currently other clinical trials evaluating the effects of SGLT2 inhibitors in obese individuals without diabetes used alone or in combination with other drugs (ClinicalTrial.gov identifier: NCT03093103, NCT03710460, NCT02635386, NCT02695810)

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19 Immunohistochemistry For paraformaldehyde (PFA) fixation, mice were deeply anesthetized with isoflurane and perfused sequentially with heparinized normal saline, followed by 4% PFA and 0.5% glutaraldehyde