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194 GLP-1 also acts directly on the liver, inhibiting glycogenolysis, promoting glycogen synthesis, and regulating the expression of lipid metabolism-associated genes, thereby reducing hepatic fat accumulation and improving glucose and lipid homeostasis along the gutliver axis
They actually work better together than separately
Transcriptomic studies have revealed that this peptide influences the expression of more than 4,000 human genes, approximately 6% of the genome
It is structurally modified to resist DPP-4 enzymatic degradation, giving it a long half-life suitable for once-weekly administration in research
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