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Multiple epidemiological studies have suggested that a healthy diet, rich in different fruits and vegetables, boosts physiological immunity and protects the body against cancer and other chronic diseases

Whether 500 mg/day achieves pharmacologically meaningful hepatic target engagement in patients with cirrhosis, where intestinal permeability, portal hypertension, and first-pass metabolism are all altered, remains unknown and is a significant uncertainty underlying the biological interpretation of this study

Lee WM et al

These medications work by mimicking the action of naturally occurring incretin hormones, which enhance glucose-dependent insulin secretion, suppress inappropriate glucagon release, slow gastric emptying, and promote satiety through central nervous system pathways