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Some older studies examined combinations of weaker GLP-1 drugs with DPP-4 inhibitors, showing modest additional glucose lowering compared to either drug alone, but the incremental benefit did not justify the added complexity and cost for most patients
Biosimilars such as Stelarsdi have been approved by the FDA for its sale in the US
Benefits of Injectable Tirzepatide: Extended Efficacy: Weekly administration provides sustained benefits
Up to 92% of people taking tirzepatide got their HbA1c levels below 7%, and over 80% reached 6.5% or below
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