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People struggling with weight loss despite lifestyle efforts
For example, estrogen signaling has been shown to enhance the anorexigenic effects of GLP-1 RAs by modulating central pathways involved in food reward, which could account for the more pronounced weight loss observed in premenopausal women [49, 50]
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10.1016/j.mehy.2020.109638 103 World Health Organization (2024)
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