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After use, the needle retracts automatically into the pen for safety
Patients on tirzepatide lost an average of 20.2% of their body weight over 72 weeks Patients on semaglutide lost an average of 13.7% of their body weight over the same period 47% more tirzepatide patients achieved 25% or greater body weight loss compared to semaglutide Tirzepatide also produced greater reductions in waist circumference across all dose comparisons A 2024 meta-analysis published in JAMA Internal Medicine analyzing real-world data from over 140,000 patients confirmed the same pattern: tirzepatide produced an average of 4.23 kg more weight loss than semaglutide across all doses and durations studied
Researchers selecting between compounds, or justifying the BPC-157 + TB-500 dosing protocol for a mixed-tissue model, can use this map to match peptide to endpoint
According to the drugs prescribing label, weight loss is typically the greatest in the first few weeks of treatment and then decreases in succeeding weeks
