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Published research has demonstrated that GHK-Cu can influence numerous genes involved in: extracellular matrix synthesis collagen turnover tissue remodelling inflammatory signalling antioxidant defence stem-cell related pathways angiogenesis Copper binding is essential to this biological activity, allowing GHK-Cu to participate in cellular signalling processes associated with tissue maintenance and repair

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Interestingly, the hypothesized Cm effectors are rare in necrotrophs and saprophytes, and is only identified in S