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339 Glycolysis Disruption of glucose metabolism is closely linked to the progression of PD, potentially because of the negative impact of impaired glucose metabolism on the DA system
Die Patienten knnen in den ersten 24 bis 48 Stunden symptomfrei sein
157,158 In addition, AMPK phosphorylates and inhibits transcription factors that stimulate glycolytic and lipogenic transcriptional processes, particularly SREBP1, a key regulator of lipid synthesis, 159 as well as hepatocyte nuclear factor-4 (HNF4) and carbohydrate-responsive element binding protein (ChREBP)
If you're concerned, measure homocysteine and methylmalonic acid (MMA) at baseline and at 12 weeks
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