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From these figures, it is clear that electron density transfers from the HOMO, which is more localized on the substrate, to the LUMO, which includes electron density on the axial Co-C and Co-O bonds and is antibonding for these bonds

Acidification will increase excretion, while alkalinization will decrease it

Moreover, NAD+ is also a key player in redox reactions, and its depletion is thought to contribute to the development of oxidative stress

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