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Given the principal anti-inflammatory effect of GLP-1 in the central nervous system elucidated in previous sections, research on the role of GLP-1 in the neuro-ophthalmic circuit shows a similar beneficial promise
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claims data from more than 1 million female patients ages 12 to 45 with a newly observed and confirmed diagnosis of PMOS (E28.2) between 2020 and 2025
Consistently, cell lines with abrogation of G2/M phase upon combination treatment, i.e., NCI-H520 and NCI-HCC15 also presented a reduction of the expression of p21 CIP/WAF1 and p-ATM, the latter involved in the DNA damage response pathway (Supplementary Figs
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