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We recently found that targeting BET proteins induces glutamate dehydrogenase 1 (GDH1)-dependent glutamine metabolic remodeling in liver cancer, where glutamine-derived -KG through GDH1 maintains cancer cell survival when glycolysis is compromised 23 , but the underlying mechanisms are not fully understood
Presented for research literature review only Gertzberg N et al
I started with 0.25 mg injected subcutaneously near my lateral malleolus each morning
Capping strategy was performed using the CAG trimer (Vazyme) in transcription
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