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Gut microbiome correlates with treatment efficacy Next, we evaluated the ability of the baseline gut microbiome to predict changes in the major clinical endpoints, indicating the efficacy of the antidiabetic therapy

However, it is difficult to ascertain whether this was due to specific biology or the lack of statistical power after adjustment for multiplicity in STEP 2 due to a smaller sample size

Side-by-side dosing comparison The most striking difference is not the starting doses or the titration timelines, which are fairly similar across all three peptides

The drug is presently in Phase III obesity clinical trials and is expected to launch by 2027