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You can read more about how a drug actually becomes approved on the FDAs drug-approval pages

2 Results and discussion 2.1 GLP-1 positive cells are consistently reduced under inflammatory conditions To comprehensively characterize the impact of intestinal inflammation on the number of GLP-1- expressing L cells in the epithelium, ileal and colonic tissue sections from different mouse models of intestinal inflammation were immunohistochemically stained ( Figure 1A )

The next question was harder: what happens when treatment is withdrawn

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