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35, 36 Mice were weighed twice weekly to assess toxicity and killed when tumors reached 1500 mm 3 or they experienced any severe morbidity (that is, body weight 2, (b) a significant difference ( P 60% were considered to have low activity
Results represent 3 independent experiments
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[6] The investigators concluded that the lipolytic actions were not explained by direct beta-3-receptor activation, although increased receptor expression could contribute to enhanced lipolytic sensitivity after longer exposure
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