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Studied in lipodystrophy and metabolic dysfunction models for depot-specific adipose tissue effects

CappelliniMDBejaouiMAgaogluLCanatanDCapraMCohenAet alIron chelation with deferasirox in adult and pediatric patients with thalassemia major: efficacy and safety during 5 years follow-up

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However, significant challenges remain, including the synthesis of stable tripeptides with good tissue penetration, insufficient understanding of their mechanisms of action, the scarcity of studies in larger animal models and human trials, and the lack of direct head-to-head comparisons with larger peptides [75, 95]