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This reflects a key limitation: GLP-1 medications can reduce appetite and support weight loss, but they do not by themselves establish a long-term metabolic framework for maintaining that loss
Cookie-cutter protocols ignoring these variables produce suboptimal outcomes, while thoughtful individualization maximizes benefits within each patient's physiologic capacity
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Today, the key question is no longer how much we lower glucose, but how we modify long-term risk: cardiovascular, renal, inflammatory, and functional
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