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The cells were collected after treatment, washed twice with cold phosphate-buffered saline, and treated with 1 mL of cold citrate buffer (0.24 M sucrose, 40 mM sodium citrate, pH 7.6)

RTKs are generally stimulated by growth factors or hormones, and these specific RTKligand interactions trigger important cellular activities, such as migration, proliferation and morphogenesis

In this cohort, Cagri induced a greater but still transient weight loss in WT animals, while in Gipr hypo-KO mice, even greater weight loss was sustained to the end of the experiment (Fig

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