Chronic high-dose use may not be wise for someone with cardiovascular disease risk, high LDL cholesterol, kidney disease, or a medical history that already warrants monitoring
Image: Galina Zhigalova/Getty Images About the Author Maureen Salamon, Executive Editor, Harvard Women's Health Watch About the Reviewer Meghan Salamon, MS, RDN, LDN, CPT, Contributor Disclaimer: As a service to our readers, Harvard Health Publishing provides access to our library of archived content
After a 2 day washout period, mice were subjected to tMCAO as described above
Pooled analysis from the SURPASS-1-5 trials showed that tirzepatide reduced urinary albumin-to-creatinine ratio (UACR) by 19-26% depending on dose, compared to all pooled comparators