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Nrf2-dependent antioxidant pathway Allicin was also found to upregulate the expression of glutamate-cysteine ligase (GCL), the rate-limiting enzyme in glutathione synthesis, and other Phase II detoxifying/antioxidant enzymes, likely via the activation of the nuclear factor E2-related factor 2 (Nrf2)-dependent pathway (19)
Accordingly, the present mini-review is intended to provide a hypothesis-generating and translational framework rather than definitive clinical guidance
Many patients qualify with a BMI of 27 or higher if they also have one or more weight-related medical conditions
It is essential for normal growth, development, and health [1]
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