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Comparative analysis of lipid metabolism between the HFD + EPA + L-carnitine group and the HFD group showed a significant increase in EPA (EPA was below detection limits in the HFD group), DHA and DPA and a significant decrease in arachidonate in the former group (20:4n-6) (Table 4)

Trends Mol Med 27:895906 Kovarik JJ, Bileck A, Hagn G, Meier-Menches SM, Frey T, Kaempf A, Hollenstein M, Shoumariyeh T, Skos L, Reiter B, Gerner MC, Spannbauer A, Hasimbegovic E, Schmidl D, Garhofer G, Gyongyosi M, Schmetterer KG, Gerner C (2023) A multi-omics based anti-inflammatory immune signature characterizes long Covid-19 syndrome

MTS assay results showed that neither A-CDs nor AA-CDs at a concentration of 0 to 100 g/mL exerted significant cytotoxicity on chondrocytes (Figure S10)

As such, substantial data on BPC-157 administration in humans is lacking