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Absolute contraindications Pregnancy and breastfeeding Age under 21 Impaired kidney function Uncontrolled hypothyroidism / active thyroid hormone therapy (caution, consultation) Concomitant use of oral coumarin anticoagulants without INR control Hypersensitivity to L-carnitine or solution components Legal status The status of injectable L-carnitine is two-tiered: the molecule is widely approved orally, but the injectable form and its route of administration are subject to a separate framework
The maintenance dose for most adults is 2.4 mg once per week
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L-carnitine protects against methotrexate-induced hepatotoxicity via regulation of [PMID: 41874608] Laboratory literature summary: L-carnitine protects against methotrexate-induced hepatotoxicity via regulation of apoptosis and metabolic pathways
