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An open-label introductory period of the first 36 weeks, during which all subjects were treated with tirzepatide, followed by a 52-week double-blind treatment period, during which subjects were randomly assigned to receive either tirzepatide or placebo
Zepbound delays gastric emptying and may impact the absorption of oral medications
That sounds backwards but it makes sense, berberine is correcting more significant dysfunction, so the payoff is proportionally larger
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