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In Phase 2 clinical research, retatrutide demonstrated body weight reductions of up to 24.2% over 48 weeks, the largest reported for any incretin-based compound at that stage of development [8]
Semaglutide makes lifestyle changes easier by reducing appetite and food preoccupation, while the lifestyle changes maximize what the medication achieves
Medicine (Baltimore) 102:e35545
Hence, treatment compliance can be improved by selecting agents that are injected once weekly such as semaglutide or dulaglutide
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