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Group 3: CRE-AgNPs treated (negative control): This group was treated with 50 mg/kg body weight of CRE-AgNPs dissolved in distilled water for 7 consecutive days once daily
Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition
-TOH curtails this cascade, reducing mitochondrial permeability transition pore (mPTP) opening and cytochrome c release, thereby attenuating apoptotic signaling [3]
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