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Because TRT Nation includes B12 in every compounded tirzepatide prescription and starts all patients at conservative doses with a slow titration schedule, most patients find that any nausea is mild and improves significantly within the first few weeks of treatment

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In such cases, the focus should shift to investigating potential underlying causessuch as myeloproliferative disorders, liver disease, or renal dysfunctionrather than attributing symptoms to the elevated B12 itself

During the appointment, the B12 shot is administered as a quick injection in a clinical setting