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Some disease states are associated with low total serum vitamin B12 concentrations because of an inability to absorb or digest protein-bound vitamin B12
Such binding may displace other regulatory proteins, making DNA more accessible for transcriptional machinery, potentially inducing neuronal cell differentiation in retinal and periodontal ligament stem cells (hPDLSCs)
Poor sleep increases hunger hormones, decreases satiety hormones, impairs insulin sensitivity, and reduces motivation for healthy behaviors
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