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You should expect noticeable appetite reduction within the first 12 weeks, with meaningful weight loss appearing over 48 weeks at therapeutic doses
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Despite their efficacy, the safety profiles of SGLT-2i and GLP-1RA, particularly concerning infectious disease risks and gastrointestinal adverse events, remain a subject of ongoing investigation [7,8,9]
When investigating B12 deficiency, it's important to check folate status as well, as the two deficiencies often coexist
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