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To assess whether these trends reflected coordinated biochemical changes rather than isolated metabolite fluctuations, we performed pathway-level analysis comparing shunt responders and non-responders ( Figure 2C )
While some people taking GLP-1 agonists experience difficult side effects, including nausea, vomiting and diarrhoea, and there is a need for more data on the impact of long-term use of these medicines, currently available data suggest that the benefits associated with GLP-1 agonists outweigh their risks
Whole blood samples were withdrawn from the jugular vein into EDTA tubes (Sarstedt, Nrnbrecht, Germany) 1520 minutes following darting and stored at 20 C in the Serengetipark
Included in the core analysis were 1822 patients treated with a GLP-1 RA and 992 individuals treated with an SGLT2i
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