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The Wegovy-NAION Link: Research Limitations and Unanswered Questions What challenges remain in establishing a definitive connection between Wegovy (Semaglutide) and the risk of Nonarteritic Anterior Ischemic Optic Neuropathy (NAION)
Semaglutide reduces appetite by directly activating GLP-1 receptors in brain regions that control hunger and satiety, independently of leptin pathways
Published clinical trials, conducted under medical supervision, also document potential side effects such as gastrointestinal side effects and, in rare cases, pancreatitis
