Clinical studies have used schedules more intensive than those seen in recovery practice: patients with Parkinson's disease received 1,400 mg three times a week for four weeks (Hauser et al., Movement Disorders 2009, PMID 19230029), while studies on skin lightening used 1,200 mg twice a week for six weeks (Alzahrani et al., Cureus 2025, PMID 40013212)
Researchers reported that the results across all three trials indicated that the peptide may have a positive correlation with exposure and melanin production, as observed on a cellular level and in the relative tanning gradation
Compared with group B, the levels of PCO 2 , HCT, K + , Cl and Hb in groups C and D were decreased, and the difference was statistically significant
3 The approval allows for a higher dose of 7.2 mg for maintenance in weight loss patients