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Encouragingly, experiments show that antioxidant interventions in aged animals (including administering melatonin or vitamin E) can restore some amplitude to circadian rhythms and improve activity/rest pattern stability (Reiter et al., 2024)
Dulaglutide (Trulicity) begins at 0.75 mg once weekly, with potential increases to 1.5 mg, 3 mg, or a maximum of 4.5 mg weekly based on glycemic response
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