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For semaglutide, included trials comprised STEP 2 [9], STEP UP-DM [10], SUSTAIN-1 through SUSTAIN-11, and SUSTAIN FORTE [11,12,13,14,15,16,17,18,19,20,21,22]
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if the medication has been frozen, it must be discarded, as freezing can denature the peptide structure and alter its appearance and function
Mounjaro faces competition from other GLP-1 RAs, notably Novo Nordisk's semaglutide, but has shown superiority in head-to-head trials
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