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The companys original version of Wegovy is a weekly injectable
Investigational Peptide Primary Search Intent: Therapeutic informational Secondary Keywords: retatrutide for weight loss
This is not simply a tolerability story it reflects an intersection of side-effect burden, inadequate weight loss response, access barriers, and cost that together create a real-world efficacy gap between what randomized controlled trials demonstrate and what clinicians observe in practice
PMID: 41770566, PMCID: PMC12954541, DOI: 10.1001/jamanetworkopen.2026.0374
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