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In parallel, metformin suppresses apoptosis by reducing the Bax/Bcl-2 ratio and caspase-3 activation (Van et al., 2023
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Figure 6 3.6 Alterations in the ultrastructure of mitochondria in the hippocampal CA1 region The occurrence of central fatigue is closely associated with cerebral energy metabolism, and the morphological structure of mitochondria can directly reflect whether mitochondrial function is normal
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