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This can lead to symptoms such as: Stomach pain or discomfort Heartburn or indigestion Nausea In severe cases, ulcers or gastrointestinal bleeding People who take ibuprofen frequently or in high doses, have a history of stomach ulcers, or are older adults are at higher risk of experiencing stomach pain or more serious complications

Caban-Toktas S, et al

[55], showed that rats, orally receiving radiolabeled LC, metabolized it to -butyrobetaine (up to 31% of the administered dose, present primary in feces) and TMAO (up to 23% of the administered dose, present primary in urine)

Prophylactic therapy of Silymarin (Milk Thistle) on antituberculosis drug-induced liver injury: a meta-analysis of randomized controlled trials