In addition to its appetite-suppressing effects, semaglutide also has metabolic benefits, improving insulin sensitivity and supporting long-term weight management
Bucinskaite V, Tolessa T, Pedersen J, Rydqvist B, Zerihun L, Holst JJ, et al
This dual action is what makes it more effective for weight loss than single-agonist drugs, but it also means the GI system is hit from two directions at once
Zachary Knight from University of California, San Francisco on to talk about GLP-1 in a lot of detail, he mentioned that some of the nausea associated with ozempic and Mounjaro and things like that relates to the fact that there are receptors for these things, not just in one hypothalamic structure, but also in area postrema and areas of the brain that are these "primitive" areas that are associated with generating nausea when you need to rid yourself of a poison that- Craig: Makes sense