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In biosimilars specifically, scale matters: the economics favor manufacturers capable of competing on both price and supply reliability simultaneously, because payers and PBMs will not accept single-source biosimilar supply after watching supply disruptions across the generic small-molecule market
The neuroprotective effects of GLP-1R agonists may be closely related to their impact on insulin resistance and glucose metabolism
Breastfeeding Considerations Limited data exists about whether tirzepatide passes into breast milk or affects nursing infants
GI tolerance is a limiting factor in Wegovy dosing, as prolonged gastrointestinal issues, such as vomiting and diarrhea, may cause dehydration, which can lead to kidney damage
