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By inhibiting GPX4 and GSS, solasonine increased the amounts of lipid ROS in HepG2 cells to produce these effects (132)

This approach leverages the abundant availability of platelets and avoids ethical concerns associated with other cell sources, representing a promising translational direction for treating cognitive deficits in diabetic populations

By improving levodopa absorption, the modulation of the GM potentially offers a wide range of benefits in PD, from optimal medication management to treatment of disabling motor symptoms secondary to peripheral levodopa resistance

These changes may lead to the development of bone cysts and lesions in the bone marrow