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The Endocrine Society's 2020 Scientific Statement on peptide hormone use noted that "the absence of drug interaction data for non-FDA-approved peptides represents a patient safety concern that clinicians should communicate explicitly" 9
Caputi S, Trubiani O, Sinjari B, Trofimova S, Diomede F, Linkova N, et al
Current trials also exclude people with diabetes, recent heart problems, and eating disorders, which may indicate future contraindications once approved
These typically resolve on their own within the first few weeks of treatment
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