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it acts together with endothelial nitric oxide synthase (eNOS) and an increase in the availability of nitric oxide (NO), which dilates vessels and improves microcirculation
In trials with patients with type 2 diabetes and overweight/obesity, after 16 weeks of treatment with Danuglipron, the high-dose (120 mg twice daily) group showed an average weight loss of 4.2 kg and a reduction in HbA1c levels by 1.2% compared to the placebo group
Furthermore, as mentioned (Luetic et al., 2017
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